Toru Obata Selected Research

Hemoperfusion

1/2018	Sphingosine-1-Phosphate (S1P) Is a Feasible Biomarker in Predicting the Efficacy of Polymyxin B-Immobilized Fiber Direct Hemoperfusion (PMX-DHP) in Patients with Septic Shock.
12/2013	The ability of endotoxin adsorption during a longer duration of direct hemoperfusion with a polymyxin B-immobilized fiber column in patients with septic shock.
1/2012	Time to initiation of treatment with polymyxin B cartridge hemoperfusion in septic shock patients.
4/2010	Effectiveness of endotoxin scattering photometry for determining the efficacy of polymyxin B-immobilized fiber treatment in septic shock: report of a case.
1/2010	Effectiveness of early start of direct hemoperfusion with polymyxin B-immobilized fiber columns judging from stabilization in circulatory dynamics in surgical treatment patients.
10/2008	Removal of 2-arachidonylglycerol by direct hemoperfusion therapy with polymyxin B immobilized fibers benefits patients with septic shock.
7/2008	Relationship between treatment resistance to hemoperfusion using a polymyxin B-immobilized fiber column and oxidative stress.
1/2008	Effectiveness of continuous hemodiafiltration using a polymethylmethacrylate membrane hemofilter after polymyxin B-immobilized fiber column therapy of septic shock.
9/2007	Clinical responses and improvement of some laboratory parameters following polymyxin B-immobilized fiber treatment in septic shock.
3/2006	Polymyxin B immobilized column is effective for hydrochloric acid-induced lung injury in rats.

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Toru Obata Research Topics

Disease

10	Septic Shock (Toxic Shock Syndrome) 01/2018 - 09/2007
4	Sepsis (Septicemia) 01/2018 - 10/2008
3	Endotoxemia 10/2010 - 01/2010
3	Lung Injury 10/2009 - 03/2006
2	Peritonitis 04/2014 - 10/2008
2	Inflammation (Inflammations) 04/2014 - 10/2010
2	Infections 04/2014 - 01/2012
1	Intraabdominal Infections 12/2013
1	Neoplasms (Cancer) 01/2012
1	Fistula 10/2009
1	Stable Angina 01/2009
1	Obesity 01/2009
1	Unstable Angina 01/2009
1	Atherosclerosis 01/2009
1	Coronary Artery Disease (Coronary Atherosclerosis) 01/2009
1	Atherosclerotic Plaque (Atheroma) 01/2009
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 07/2008
1	Acute Lung Injury 07/2008
1	Critical Illness (Critically Ill) 01/2008

Drug/Important Bio-Agent (IBA)

10	Polymyxin B (Aerosporin)FDA LinkGeneric 01/2018 - 03/2006
5	EndotoxinsIBA 12/2013 - 04/2010
3	anandamide (arachidonylethanolamide)IBA 08/2009 - 10/2008
2	Biomarkers (Surrogate Marker)IBA 01/2018 - 10/2008
2	DinoprostIBA 10/2009 - 10/2008
2	Biological ProductsIBA 08/2009 - 10/2008
2	EndocannabinoidsIBA 01/2009 - 10/2008
2	F2-Isoprostanes (F2 Isoprostanes)IBA 10/2008 - 07/2008
1	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 01/2018
1	lipoxin A4IBA 04/2014
1	Anti-Bacterial Agents (Antibiotics)IBA 04/2014
1	Ceftazidime (Fortum)FDA LinkGeneric 04/2014
1	ProcalcitoninIBA 12/2013
1	CatecholaminesIBA 01/2012
1	C-Reactive ProteinIBA 01/2012
1	LipopolysaccharidesIBA 10/2010
1	Oleic Acid (Oleate)IBA 10/2009
1	IsoprostanesIBA 10/2009
1	CathelicidinsIBA 08/2009
1	GalactosamineIBA 08/2009
1	HMGB1 Protein (HMG1)IBA 08/2009
1	Peptides (Polypeptides)IBA 08/2009
1	CytokinesIBA 08/2009
1	Messenger RNA (mRNA)IBA 01/2009
1	LipidsIBA 01/2009
1	RimonabantIBA 01/2009
1	CB1 Cannabinoid Receptor (CB1 Receptor)IBA 01/2009
1	Glycerol (Glycerine)FDA LinkGeneric 01/2009
1	CannabinoidsIBA 01/2009
1	glyceryl 2-arachidonate (2-arachidonoylglycerol)IBA 10/2008
1	Polymethyl Methacrylate (Sol)IBA 01/2008
1	Plasminogen Activator Inhibitor 1IBA 09/2007
1	Hydrochloric Acid (Hydrogen Chloride)FDA Link 03/2006

Therapy/Procedure

10	Hemoperfusion 01/2018 - 03/2006
3	Therapeutics 04/2014 - 01/2008
1	Aftercare (After-Treatment) 01/2018
1	Mechanical Ventilators (Ventilator) 01/2012
1	Renal Dialysis (Hemodialysis) 10/2010
1	Vascular Access Devices (Arterial Line) 10/2009
1	Laparotomy 10/2008
1	Hemodiafiltration 01/2008